World Journal of Endocrine Surgery

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VOLUME 11 , ISSUE 2 ( May-August, 2019 ) > List of Articles

Original Article

Treatment Outcomes of Transperitoneal Laparoscopic Adrenalectomy in Patients with Functional Adrenal Gland Tumors

Kriangsak Jenwitheesuk, Kamonwan Jenwitheesuk, Suriya Punchai, Jakrapan Wittayapairoch

Keywords : Functional adrenal gland tumor, Transperitoneal approach, Transperitoneal laparoscopic adrenalectomy, Treatment outcomes

Citation Information : Jenwitheesuk K, Jenwitheesuk K, Punchai S, Wittayapairoch J. Treatment Outcomes of Transperitoneal Laparoscopic Adrenalectomy in Patients with Functional Adrenal Gland Tumors. World J Endoc Surg 2019; 11 (2):41-45.

DOI: 10.5005/jp-journals-10002-1258

License: CC BY-NC 4.0

Published Online: 01-08-2019

Copyright Statement:  Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Background: Functional adrenal gland tumor is a tumor that presents with abnormal producing excess aldosterone hormone and affects the functionality of renin angiotensin aldosterone system which can be treated by laparoscopic adrenalectomy. The adrenal surgery can be approached in many techniques, such as transperitoneal and retroperitoneal approach. Materials and methods: The inclusion criterion was all patients who had diagnosed with functional adrenal gland tumor underwent laparoscopic adrenalectomy since 2011–2017 at the Srinagarind Hospital, the Faculty of Medicine, Khon Kaen University, Thailand. Patients with a lesion more than 8 cm and patients with suspected metastatic lesions were excluded. Baseline clinical features, results of clinical evaluation, pathology, operative reports, and outcome of treatment were recorded. Results: Seventy patients were treated with transperitoneal laparoscopic adrenalectomy. There were 18 men and 52 women. Mean age was 46.30 ± 11.88 years. All patients were presented with hypertension and 7 cases were presented with hypokalemia. Major histologic finding was adenoma. The mean operating time was 99.29 ± 45.66 minutes, estimated blood loss 82.36 ± 202.14 mL, and mean postoperative length of stay was 3.80 ± 2.34 days. Complications were occurred in six patients. Conclusion: Transperitoneal laparoscopic surgery had good outcomes for functional adrenal gland tumor.


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  1. Gagner M, Lacroix A, et al. Laparoscopic adrenalectomy in Cushing's syndrome and pheochromocytoma. N Engl J Med 1992 Oct;327(14):1033. DOI: 10.1056/NEJM199210013271417.
  2. Del Pizzo JJ. Transabdominal laparoscopic adrenalectomy. Curr Urol Rep 2003 Feb;4(1):81–86. DOI: 10.1007/s11934-003-0064-5.
  3. Mellon MJ, Sethi A, et al. Laparoscopic adrenalectomy: Surgical techniques. Indian J Urol 2008 Oct-Dec;24(4):583–589. DOI: 10.4103/0970-1591.44277.
  4. Nakagawa K, Murai M. Laparoscopic adrenalectomy: current status with a review of Japanese literature. Biomed Pharmacother 2002;56(1):107s–112s. DOI: 10.1016/S0753-3322(02)00232-9.
  5. Lezoche E, Guerrieri M, et al. Perioperative results of 214 laparoscopic adrenalectomies by anterior transperitoneal approach. Surg Endosc 2008 Feb;22(2):522–526. DOI: 10.1007/s00464-007-9555-7.
  6. Paganini AM, Guerrieri M, et al. Management of adrenal incidentaloma by laparoscopic transperitoneal anterior and submesocolic approach. Langenbecks Arch Surg 2016 Feb;401(1):71–79. DOI: 10.1007/s00423-015-1367-y.
  7. Conzo G, Tartaglia E, et al. Minimally invasive approach for adrenal lesions: Systematic review of laparoscopic versus retroperitoneoscopic adrenalectomy and assessment of risk factors for complications. Int J Surg 2016 Apr;28(1):S118–S123. DOI: 10.1016/j.ijsu.2015.12.042.
  8. Gasman D, Droupy S, et al. Laparoscopic adrenalectomy: the retroperitoneal approach. J Urol 1998 Jun;159(6):1816–1820. DOI: 10.1016/S0022-5347(01)63163-X.
  9. Chai YJ, Woo JW, et al. Comparative outcomes of lateral transperitoneal adrenalectomy versus posterior retroperitoneoscopic adrenalectomy in consecutive patients: a single surgeon's experience. Asian J Surg 2016 Apr;39(2):74–80. DOI: 10.1016/j.asjsur.2015.04.005.
  10. Constantinides VA, Christakis I, et al. Systematic review and meta-analysis of retroperitoneoscopic versus laparoscopic adrenalectomy. Br J Surg 2012 Dec;99(12):1639–1648. DOI: 10.1002/bjs.8921.
  11. Poulose BK, Holzman MD, et al. Laparoscopic adrenalectomy: 100 resections with clinical long-term followup. Surg Endosc 2005 Mar;19(3):379–385. DOI: 10.1007/s00464-004-8914-x.
  12. Zhou Y, Zhang M, et al. Hypertension outcomes of adrenalectomy in patients with primary aldosteronism: a systematic review and meta-analysis. BMC Endocr Disord 2017 Oct;17(1):61. DOI: 10.1186/s12902-017-0209-z.
  13. Gupta PK, Natarajan B, et al. Outcomes after laparoscopic adrenalectomy. Surg Endosc 2011 Mar;25(3):784–794. DOI: 10.1007/s00464-010-1256-y.
  14. Palazzo FF, Sebag F, et al. Long-term outcome following laparoscopic adrenalectomy for large solid adrenal cortex tumors. World J Surg 2006 May;30(5):893–898. DOI: 10.1007/s00268-005-0288-2.
  15. Gagner M, Pomp A, et al. Laparoscopic adrenalectomy: lessons learned from 100 consecutive procedures. Ann Surg 1997 Sep;226(3):238–246. DOI: 10.1097/00000658-199709000-00003.
  16. Dickson PV, Alex GC, et al. Posterior retroperitoneoscopic adrenalectomy is a safe and effective alternative to transabdominal laparoscopic adrenalectomy for pheochromocytoma. Surgery 2011 Sep;150(3):452–458. DOI: 10.1016/j.surg.2011.07.004.
  17. Li H, Liu J, et al. Favorable surgical outcomes of aldosterone-producing adenoma based on lateralization by CT imaging and hypokalemia: a non-AVS-based strategy. Int Urol Nephrol 2017 Dec;49(12):2151–2156. DOI: 10.1007/s11255-017-1705-9.
  18. Christakis I, Livesey JA, et al. Laparoscopic Adrenalectomy for Conn's Syndrome is Beneficial to Patients and is Cost Effective in England. J Invest Surg 2017 May;12:1–7.
  19. Brunt LM, Moley JF, et al. Outcomes analysis in patients undergoing laparoscopic adrenalectomy for hormonally active adrenal tumors. Surgery 2001 Oct;130(4):629–634. DOI: 10.1067/msy.2001. 116920.
  20. Wu CH, Er LK, et al. Is Laparoendoscopic Single-Site Adrenalectomy a Feasible Alternative in Treating Aldosterone-Producing Adenoma? Biomed Res Int 2016;2016:6894381.
  21. Jiang SB, Guo XD, et al. A retrospective study of laparoscopic unilateral adrenalectomy for primary hyperaldosteronism caused by unilateral adrenal hyperplasia. Int Urol Nephrol 2014 Jul;46(7):1283–1288. DOI: 10.1007/s11255-013-0614-9.
  22. Ali JM, Liau SS, et al. Laparoscopic adrenalectomy: auditing the 10 year experience of a single centre. Surgeon 2012 Oct;10(5):267–272. DOI: 10.1016/j.surge.2011.08.003.
  23. O'Boyle CJ, Kapadia CR, et al. Laparoscopic transperitoneal adrenalectomy. Surg Endosc 2003 Dec;17(12):1905–1909. DOI: 10.1007/s00464-002-8878-7.
  24. Campagnacci R, Crosta F, et al. Long-term results of laparoscopic adrenalectomy for primary aldosteronism. J Endocrinol Invest 2009 Jan;32(1):57–62. DOI: 10.1007/BF03345680.
  25. Lin Y, Li L, et al. Experience of retroperitoneoscopic adrenalectomy in 195 patients with primary aldosteronism. Int J Urol 2007 Oct;14(10):910–913. DOI: 10.1111/j.1442-2042.2007.01860.x.
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