Bilateral Level I Lymphadenopathy in Differentiated Thyroid Carcinoma: A Case Report and Review of Literature
Sasi Mouli V, M Shreyamsa
Citation Information :
V SM, Shreyamsa M. Bilateral Level I Lymphadenopathy in Differentiated Thyroid Carcinoma: A Case Report and Review of Literature. World J Endoc Surg 2020; 12 (1):41-44.
Lymph nodal metastases in differentiated thyroid cancers (DTC) occur in 30–90% of all cases.1 A major question remains about the therapeutic benefits of a more or less extensive lateral lymphadenectomy as metastases to levels I and V are infrequent, and extensive dissections may add to the morbidity. We herein report a case of papillary carcinoma thyroid with bilateral level I–V lymph node metastases.
Kebebew E, Clark OH. Differentiated thyroid cancer: “complete” rational approach. World J Surg 2000;24(8):942–951. DOI: 10.1007/s002680010165.
Eskander A, Merdad M, Freeman JL, et al. Pattern of spread to the lateral neck in metastatic well-differentiated thyroid cancer: a systematic review and meta-analysis. Thyroid 2013;23(5):583–592. DOI: 10.1089/thy.2012.0493.
Shaha AR. Prognostic factors in papillary thyroid carcinoma 17. And implications of large nodal metastasis. Surgery 2004;135(2):237–239. DOI: 10.1016/j.surg.2003.08.023.
Haugen BR, Alexander EK, Bible KC, et al. 2015 American thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the american thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid 2016;26(1):1–133. DOI: 10.1089/thy.2015.0020.
Sivanandan R, Soo KC. Pattern of cervical lymph node metastases from papillary carcinoma of the thyroid. Br J Surg 2001;88(9): 1241–1244. DOI: 10.1046/j.0007-1323.2001.01843.x.
Kupferman ME, Patterson M, Mandel SJ, et al. Patterns of lateral neck metastasis in papillary thyroid carcinoma. Arch Otolaryngol Head Neck Surg 2004;130(7):857–860. DOI: 10.1001/archotol.130.7.857.
Caron NR, Tan YY, Ogilvie JB, et al. Selective modified radical neck dissection for papillary thyroid cancer—is level I, II and V dissection always necessary? World J Surg 2006;30(5):833–840. DOI: 10.1007/s00268-005-0358-5.
Eweida AM, Sakr MF, Hamza Y, et al. Level I lymph node involvement in patients with N1b papillary thyroid carcinoma: a prospective study. Eur Arch Otorhinolaryngol 2017;274(4):1951–1958. DOI: 10.1007/s00405-016-4423-5.
Roh JL, Kim JM, Park CI. Lateral cervical lymph node metastases from papillary thyroid carcinoma: pattern of nodal metastases and optimal strategy for neck dissection. Ann Surg Oncol 2008;15(4):1177–1182. DOI: 10.1245/s10434-008-9813-5.
Nam IC, Park JO, Joo YH, et al. Pattern and predictive factors of regional lymph node metastasis in papillary thyroid carcinoma: a prospective study. Head Neck 2013;35(1):40–45. DOI: 10.1002/hed.22903.
Ahmadi N, Grewal A, Davidson DJ. Patterns of cervical lymph node metastases in primary and recurrent papillary thyroid cancer. J Oncol 2011;2011:735678. DOI: 10.1155/2011/735678.
Suh CH, Baek JN, Choi YJ, et al. Performance of CT in the preoperative diagnosis of cervical lymph node metastasis in patients with papillary thyroid cancer: a systematic review and meta-analysis. Am J Neuroradiol 2016;38(1):154–161. DOI: 10.3174/ajnr.A4967.
Lan X, Sun W, Zhang H, et al. A meta-analysis of central lymph node metastasis for predicting lateral involvement in papillary thyroid carcinoma. Otolaryngology Head Neck Surg 2015;153(5):731–738. DOI: 10.1177/0194599815601412.
Batstone MD, Scott B, Lowe D, et al. Marginal mandibular nerve injury during neck dissection and its impact on patient perception of appearance. Head Neck 2009;31(5):673–678. DOI: 10.1002/hed.21013.
