World Journal of Endocrine Surgery

Register      Login

VOLUME 11 , ISSUE 2 ( May-August, 2019 ) > List of Articles

Original Article

Role of Imprint Cytology in Diagnosis of Thyroid Lesions

Abilash K Prasad, Chellaiah Petchiappan Ganesh Babu, Chetan Anand, Kathirvelu Shanmugasamy

Keywords : Cytology, Imprint cytology, Thyroid

Citation Information : Prasad AK, Babu CP, Anand C, Shanmugasamy K. Role of Imprint Cytology in Diagnosis of Thyroid Lesions. World J Endoc Surg 2019; 11 (2):49-52.

DOI: 10.5005/jp-journals-10002-1260

License: CC BY-NC 4.0

Published Online: 01-11-2019

Copyright Statement:  Copyright © 2019; The Author(s).


Abstract

Background: Thyroid disorders are common in India. Rapid and accurate intraoperative diagnosis of thyroid lesions helps in deciding the plan of management and spares the patient the additional expenses and morbidity of a second surgery. Aim: To assess the role of imprint cytology in the diagnosis of thyroid lesions in consecutive thyroidectomy specimens. A cross-sectional study was done at the Mahatma Gandhi Medical College and Research Institute, Puducherry. The study period was between November 2015 and July 2017 during which 60 consecutive thyroidectomy specimens were subjected to touch imprint cytology by the same pathologist who was blinded of the prior fine needle aspiration cytology reports, and the results of imprint cytology and fine needle aspiration cytology were compared with the final histopathological examination report. The data obtained were entered in MS Excel sheet and analyzed. Results: A total of 60 consecutive thyroid specimens from the Departments of General Surgery and ENT were studied. Imprint cytology had a sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of 61.5%, 97.9%, 88.8%, 90.1%, and 90%, respectively, which was found to be better compared to fine needle aspiration cytology. Conclusion: Imprint cytology is a simple, cheap, and reliable intraoperative diagnostic technique for thyroid lesions. It has high specificity, positive predictive value, negative predictive value, and accuracy. The lack of uniform availability and expense remains a limiting factor for the frozen section. The diagnostic indices of imprint cytology were found to be comparable to that of frozen section in various other studies.


HTML PDF Share
  1. Hajmanoochehri F, Rabiee E. FNAC accuracy in diagnosis of thyroid neoplasms considering all diagnostic categories of the Bethesda reporting system: A single-institute experience. J Cytol 2015 Dec;32(4):238–243. DOI: 10.4103/0970-9371.171234.
  2. Ozdemir D, Bestepe N, et al. Comparison of thyroid fine needle aspiration biopsy results before and after implementation of Bethesda classification. Cytopathology 2017 Oct;28(5):400–406. DOI: 10.1111/cyt.12437.
  3. Bagga PK, Mahajan NC. Fine needle aspiration cytology of thyroid swellings: how useful and accurate is it? Indian J Cancer 2010 Dec;47(4):437–442. DOI: 10.4103/0019-509X.73564.
  4. Ahmadinejad M, Aliepour A, et al. Fine-Needle Aspiration, Touch Imprint, and Crush Preparation Cytology for Diagnosing Thyroid Malignancies in Thyroid Nodules. Indian J Surg 2015 Dec;77(Suppl 2): 480–483. DOI: 10.1007/s12262-013-0882-8.
  5. Lngegowda JB, Muddegowda PH, et al. Application of pattern analysis in fine needle aspiration of solitary nodule of thyroid. J Cytol 2010 Jan;27(1):1–7. DOI: 10.4103/0970-9371.66688.
  6. Anila KR, Krishna G. Role of imprint cytology in intra operative diagnosis of thyroid lesions. Gulf J Oncolog 2014 Jul;1(16): 73–78.
  7. Chehrei A, Ahmadinejad M, et al. Touch imprint and crash preparation intra operative cytology vs frozen section in thyroid nodule. J Res Med Sci 2012 May;17(5):475–480.
  8. Taneri F, Poyraz A, et al. Using imprint and frozen sections in determining the surgical strategies for thyroid pathologies. Endocr Regul 2001 Jun;35(2):71–74.
  9. Rupp M, Ehya H. Nuclear grooves in the aspiration cytology of papillary carcinoma of the thyroid. Acta Cytol 1989 Feb;33(1): 21–26.
  10. Trosman SJ, Bhargavan R, et al. The contemporary utility of intraoperative frozen sections in thyroid surgery. Am J Otolaryngol 2017 Oct;38(5):614–617. DOI: 10.1016/j.amjoto.2017.07.003.
  11. Prades J-M, Querat C, et al. Thyroid nodule surgery: predictive diagnostic value of fine-needle aspiration cytology and frozen section. Eur Ann Otorhinolaryngol Head Neck Dis 2013 Sep;130(4): 195–199. DOI: 10.1016/j.anorl.2012.12.005.
  12. Cetin B, Aslan S, et al. Frozen section in thyroid surgery: Is it a necessity? Can J Surg 2004 Feb;47(1):29–33.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.