Neuroblastoma in Late Adolescence: Case Report and Review of Literature
Pooja Ramakant, Shreyamsa Manjunath, Sasi Mouli
Keywords :
Adrenal tumor, Late adolescence, Neuroblastoma, Sympathetic nervous system tumors
Citation Information :
Ramakant P, Manjunath S, Mouli S. Neuroblastoma in Late Adolescence: Case Report and Review of Literature. World J Endoc Surg 2018; 10 (3):157-162.
Neuroblastoma is an embryonal cancer of the peripheral sympathetic nervous system. It is the most common extracranial tumor of childhood and the third most common tumor overall. Neuroblastoma arises from cells of primordial neural crest. The natural history of this disease is very heterogeneous and extends from spontaneous regression to aggressive metastatic disease. Neuroblastoma in older children is extremely rare and it carries a bad prognosis. We present a case of a 15-year-old boy with unresectable neuroblastoma who was subjected to neoadjuvant chemotherapy which rendered the tumor resectable. The case highlights importance of neoadjuvant therapy in neuroblastomas, need for multimodality involvement and therapeutic challenges faced by phycisians in successfully treating aggressive neuroblastomas.
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