World Journal of Endocrine Surgery

Register      Login

VOLUME 11 , ISSUE 1 ( January–April, 2019 ) > List of Articles


Black Adrenal Adenoma: is it Unusual?

Nandita Chaudhary, Mallika Danda, Suneel Mattoo, Pallavi Prasad, Amit Agarwal

Keywords : Adrenal adenoma, Cushing's syndrome, Thyroid surgery

Citation Information : Chaudhary N, Danda M, Mattoo S, Prasad P, Agarwal A. Black Adrenal Adenoma: is it Unusual?. World J Endoc Surg 2019; 11 (1):33-35.

DOI: 10.5005/jp-journals-10002-1253

License: CC BY-NC 4.0

Published Online: 01-12-2018

Copyright Statement:  Copyright © 2019; The Author(s).


A 21 years old lady presented with swelling of feet and face. Weight gain and stretch marks with cushingoid features on examination with hirsutism and she had a right adrenal adenoma measuring 3 × 2.5 × 1.5 cm which was black colored. We discuss this black colored adenoma in this image of interest.

  1. Lam K-Y, Wat M-S. Adrenal cortical black adenoma: report of two cases and review of the literature. J Urol Pathol 1996;4:183–190. DOI: 10.1002/(SICI)1096-9926(199610)54:4<183::AID-TERA2>3.0.CO;2-2.
  2. Macadam RF. Black adenoma of the human adrenal cortex. Cancer 1971;27:116–119.
  3. Damron TA, Schelper RL, et al. Cytochemical demonstration of neuromelanin in black pigmented adrenal nodules. Am J Clin Pathol 1987;87:334–341.
  4. Sienkowski IK, Watkins RM, et al. Primary tumours aldosteronism due to a black adrenal adenoma. A light and electron microscopic study. J Clin Pathol 1984;37:143–149.
  5. Komiya I, Takasu N, et al. Black (or brown) adrenal cortical adenoma. Its characteristic features on computed tomography and endocrine data. J Clin Endocrinol Metab 1985;61:711–717. DOI: 10.1210/jcem-61- 4-711.
  6. Yu R, Wei M, et al. Black adrenal adenoma causing Cushing's syndrome: 40 years ago and today. Endocrinologia y nutricion: organo de la Sociedad Espanola de Endocrinologia y Nutricion 2015;62(9):466–469. DOI: 10.1016/j.endonu.2015.05.002.
  7. Ueda Y, Tanaka H, et al. A functioning black adenoma of the adrenal gland. Intern. Med. 1997;36(6):398–402.
  8. Cohen RJ, Brits R, et al. Primary hyperaldosteronism due to a functional black (pigmented) adenoma of the adrenal cortex. Arch Pathol Lab Med 1991;115(8):813–815.
  9. Tanaka S, Tanabe A, et al. Glucocorticoid-and Androgen-Secreting Black Adrenocortical Adenomas: Unique Cause of Corticotropin- Independent Cushing Syndrome. Endocr Pract 2011;17(3): e73–e78.
  10. Prince EA, Yoo DC, et al. CT and PET appearance of a pigmented “black” adrenal adenoma in a patient with lung cancer. Clin Radiol 2007;62(12):1229–1231. DOI: 10.1016/j.crad.2007.04.022.
  11. Nakajo M, Nakajo M, et al. A black adrenal adenoma difficult to be differentiated from a malignant adrenal tumor by CT, MRI, scintigraphy and FDG PET/CT examinations. Ann Nucl Med 2011;25(10):812–817. DOI: 10.1007/s12149-011-0535-6.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.