World Journal of Endocrine Surgery

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VOLUME 11 , ISSUE 3 ( September-December, 2019 ) > List of Articles

CASE REPORT

Clinical Analysis of Primary Hepatic Neuroendocrine Tumors: Presentation of a Case Report with Intraoperative Carcinoid Crisis and Review of Current Literature

Wojciech M Korcz, Paweł Nyckowski, Gustaw Lech, Michał Mazurkiewicz, Alicja Kwiatkowska, Maciej Słodkowski

Keywords : Carcinoid, Liver, Neuroendocrine tumor, Primary hepatic neuroendocrine tumor

Citation Information : Korcz WM, Nyckowski P, Lech G, Mazurkiewicz M, Kwiatkowska A, Słodkowski M. Clinical Analysis of Primary Hepatic Neuroendocrine Tumors: Presentation of a Case Report with Intraoperative Carcinoid Crisis and Review of Current Literature. World J Endoc Surg 2019; 11 (3):94-99.

DOI: 10.5005/jp-journals-10002-1265

License: CC BY-NC 4.0

Published Online: 01-06-2015

Copyright Statement:  Copyright © 2019; The Author(s).


Abstract

Introduction: Primary hepatic neuroendocrine tumor (PHNET) is extremely rare and infrequently reported in the literature. Due to the rarity and often asymptomatic clinical features, the diagnosis of PHNET preoperatively is difficult. The aim of the study was to characterize the clinical view, diagnostic tools, and results of surgical treatment of PHNETs. Materials and methods: We report PHNET case with an intraoperatively carcinoid crisis, which is a little-described complication of neuroendocrine tumors (NETs) and can be life-threatening. Published PHNET case series were searched in the PubMed, Medline, and Cochrane Library databases using combinations of relevant terms and were enclosed in the review of the literature. Case Description: A 41-year-old woman was referred due to liver mass incidentally discovered on abdominal ultrasound. The patient underwent resection of hepatic segments: II, III, IVb, V, and cholecystectomy with suddenly hemodynamic instability during surgery. Immunohistochemical and pathological examinations revealed a NETs. Conclusion: This case is interesting because of the rarity of this neoplasm and unexpected life-threatening complications. Primary hepatic neuroendocrine carcinoma should be considered as a possible differential diagnosis in the management of hepatic tumors.


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